Zithromax - how with it.

uses of Zithromax Zithromax is an antibiotic ( macrolide-type ) used to treat a wide variety of bacterial infections. It works by stopping growth of bacteria.

This antibiotic treats only bacterial infections. It'll not work for viral infections ( e. g. , common cold, flu ) . Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

how to use of Zithromax Take Zithromax by mouth with or without food, usually once a day, or as directed by your doctor. You may take Zithromax with food if stomach upset occurs.

Antibiotics work best when amount of medicine in your body is kept at a constant level. Therefore, take Zithromax at same time each day.

Continue to take Zithromax until full prescribed amount is finished even if symptoms disappear after a few days. Stopping medication too early may allow bacteria to continue to grow, which may result in a relapse of infection.

Antacids may decrease absorption of Zithromax. If you take an antacid, wait at least 2 hours after taking this medication.

Inform your doctor if your condition persists or worsens.

side effects of Zithromax Stomach upset, diarrhea/loose stools, nausea, vomiting, or stomach/abdominal pain may occur while use Zithromax. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed Zithromax because he or she has judged that benefit to we is greater than risk of side effects. Many people using Zithromax don't have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

Tell your doctor immediately if any of these highly unlikely but very serious side effects occur:

Seek immediate medical attention if any of these rare but very serious side effects occur:

Zithromax may rarely cause a severe intestinal condition ( pseudomembranous colitis ) due to a resistant bacteria. This condition may occur while use Zithromax weeks after treatment has stopped. Don't use anti-diarrhea products or narcotic pain medications if you have following symptoms because these products may make them worse. Tell your doctor immediately if we develop: persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool.

Use of Zithromax for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection ( oral or vaginal fungal infection ) . Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.

A serious allergic reaction to Zithromax is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include:

An allergic reaction to Zithromax may return even if we stop the drug. If you have an allergic reaction, continue to watch for any of the above symptoms for several days after your last dose.

This isn't a complete list of possible side effects. If we notice other effects not listed above, contact your doctor or pharmacist.

precautions of Zithromax Before taking Zithromax, tell your doctor or pharmacist if we are allergic to it; or to other macrolide antibiotics such as erythromycin, clarithromycin; or if we have any other allergies.

Before using Zithromax, tell your doctor or pharmacist your medical history, especially of:

Zithromax should be used only when clearly needed during pregnancy. Discuss risks and benefits with your doctor.

Zithromax passes into breast milk. Consult your doctor before breast-feeding.

interactions of Zithromax See also the How to Use section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring we for them. Do not start, stop, or change dosage of any medicine before checking with them first.

Before using Zithromax, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

Zithromax may decrease effectiveness of combination-type birth control pills. This can result in pregnancy. We may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.

Other drugs besides Zithromax which may affect heart rhythm ( QTc prolongation in the EKG ) include amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, propafenone, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for more details, and for instructions on how you may reduce your risk of this effect.

This document doesn't contain all possible interactions. Therefore, before using Zithromax, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share list with your doctor and pharmacist.

overdose of Zithromax If overdose of Zithromax is suspected, contact your local poison control center or emergency room immediately. US residents can call US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: severe or persistent diarrhea.

notes of Zithromax Do not share Zithromax with others.

Zithromax has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases.

missed dose of Zithromax If we miss a dose Zithromax, use it as soon as we remember. If it is near time of next dose, skip missed dose and resume your usual dosing schedule. Don't double the dose of Zithromax to catch up.

storage of Zithromax Store Zithromax at room temperature between 59-86 degrees F ( 15-30 degrees C ) away from light and moisture. Do not store Zithromax in the bathroom. Keep all medicines away from children and pets.

Properly discard Zithromax when it's expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Compare prices for Zithromax

Syphilis Makes A Comeback, UK

" Doctors were yesterday warned of an alarming rise in syphilis in UK', The Sun reports. The Independent covered same story, saying that specialists from Centers for Disease Control and Prevention in US have said that cases of disease are soaring in high-income countries. It adds that number of cases in the UK jumped from 307 in 1997 to 3, 702 in 2006, " an increase of 1, 200 per cent'.

The Times reports that, despite being nearly wiped out in developed world a decade ago, disease has had a resurgence, " in part driven by increases in cases among men who have sex with men [and] more recent increases among heterosexual people'. Most of the newspapers report that the specialists have warned that doctors now lack experience of syphilis and need training to deal with disease.

The stories are based on a review in which the authors carried out a comprehensive overview of published literature on transmission and rates of syphilis in Western Europe and the USA between 2000 and 2007. The authors discuss various explanations for changing rates of the disease and give an expert opinion on the current standards in diagnosis and treatment.

The journal that this paper was published in is prestigious and experience and knowledge and of authors is clear; this suggests that this is a reliable review and that cases of infectious syphilis are increasing.

Where did story come from?

The review was written by Dr Kevin Fenton from National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention at Centers for Disease Control and Prevention in Atlanta and colleagues from around US. The study was supported by a grant from National Institute of Health and the National Institute of Allergy and Infectious Diseases. The review was published in The Lancet Infectious Diseases, a peer-reviewed medical journal.

What kind of scientific study was this?

The authors of this non-systematic narrative review searched two databases for all research articles published between 2000 and 2007 on infectious syphilis. Earlier publications and books that were commonly referenced and highly regarded were also included.

Syphilis is a sexually transmitted infection ( STI ) caused by spiral-shaped bacterium ( spirochaete ) : treponema pallidum. The infection has two stages, primary and secondary. During the primary stage lesions ( sores and rash ) appear on the skin. These are very infectious and most cases of venereal syphilis are contracted through direct sexual contact with a person who has active syphilis. About 50% of people in direct sexual contact with someone who has active infection will develop syphilis. Infected mothers can also pass on syphilis to their unborn babies through the placenta. Transmission by other means, such as non-sexual close contact with an infected person and accidental infection by blood from needles, is less common.

Primary syphilis refers to first infection, which usually shows as a lump or ulcer at site of contact two to six weeks after infection. Secondary syphilis refers to later symptoms and signs of the disease, which usually follow healing of the first infection by six months or more. This secondary infection results from the multiplication and spread of the bacteria throughout body and can be expected to show different rates in community than primary infection, depending on how successful treatment has been. Treatment with penicillin has been available for 50 years and is effective at eliminating bacterium.

What were the results of study?

Among the facts that are reported in this review, researchers mention that rates of infectious syphilis fell to their lowest levels in many European Union countries by early 1990s.

By 1995, all reporting European countries ( except Germany ) had fewer than 300 recorded cases of infectious syphilis. However, this figure steadily rose across Europe until, around 2000, various countries began reporting increases. Belgium reported a more than three-fold increase in cases between 2000 and 2002, and cases in Austria steadily increased from a low point of 124 in 1993 to 420 in 2002. Current rates of syphilis in UK are not given in this paper.

The researchers said there have been 'alarming recent trends' in relatively wealthy parts of globe with 'huge' increases in urban centres such as London, predominantly among populations of men who have sex with men. These increases were initially observed in cities and later in suburban and rural settings.

They provided maps of rates of primary and secondary syphilis in different US states in 2003 and the trends observed between 1963 and 2003. The researchers were particularly interested in rise and fall of the rates of syphilis infection over time. Two explanations seemed likely for this pattern: either syphilis rates were varying as a result of interactions between syphilis bug and a population's immunity, or alternatively, syphilis epidemics were part of a cycle determined by infectious nature of disease.

To look at this further they produced mathematical models using data from different time periods. They found that overall number of patients with primary and secondary syphilis showed a different pattern in the populations who remained untreated, compared to those where 30% of cases were treated. These rates also varied depending on whether population modelled had either five or forty sexual partners per year. The results from these models suggested that current incidence rates aren't part of a cycle due to infectious nature of disease, but are the result of changing immunity ( such as occurs with HIV/AIDS ) .

What interpretations did the researchers draw from these results?

The researchers call for concerted public health action. They say that recent increase in syphilis among men who have sex with men and some high-risk heterosexual couples " raises cause for concern, and demands renewed vigilance among, and training of, healthcare professionals'.

They also ask for new diagnostic tools, social network approaches and new initiatives in prevention, monitoring and evaluation treatment for this disease.

What does the NHS Knowledge Service make of this study?

This comprehensive overview contains sections that describe the biology, history, diagnosis, treatment and control of syphilis. It also summarises what's known about the transmission of the disease and what influences this transmission.

Current rates of syphilis in UK aren't given in this paper. However, they can be expected to follow trends in other European countries. Other sources quoted by The Independent suggest that UK rates have jumped from 307 cases in 1997 to 3, 702 in 2006, an increase of 1, 200 per cent.

It's not clear how the references were selected for inclusion or assessed for quality, but experience and knowledge of authors is clear and suggests that this is a reliable review.

Links to headlines

Syphilis makes a comeback but doctors may not know it. The Times, March 18 2008 Doctors 'need syphilis training'. Channel 4, March 18 2008 Rise in 'high-risk' sex sees cases of syphilis soar by 1, 200 per cent. The Independent, March 18 2008

Links to science

Infectious syphilis in high-income settings in 21st century. Fenton KA, Breban R, Vardavas R, et al. The Lancet Infectious Diseases 2008; 8: 244-253

This news comes from NHS Choices

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Syphilis Makes A Comeback, UK Zithromax - how with it. Compare prices for Zithromax Possible Botulism Risk: New Era Expands Recal. New Era Canning Company, New Era, Mich., is expanding its product recall because of potential Clostridium botulinum contamination to all canned green beans and garbanzo beans distributed by the company nationwide over the last five years Explore health advises and choose right way.